Myths and facts about bone marrow donation

2019 ,اگست 26

FACT: Donating is less painful than you probably think.

Many mistakenly believe that donating blood stem cells is painful, when in reality it’s not.

While TV shows and movies have wildly exaggerated blood stem cell donation—especially bone marrow donation—as something scary, the reality is much less dramatic.

Discomfort during recovery varies from person to person. Side effects may include back pain, fatigue, headache or bruising for a few days or weeks.

The vast majority of donors say it was worth it to help save a life, and they would do it again.

Linda, marrow donor

FACT: Most blood stem cell donors give peripheral blood stem cells—a process similar to donating plasma.

Some think that the only way to donate blood stem cells is through a surgical procedure. The reality is that 77% of donations are peripheral blood stem cells, which involves no surgery at all!

PBSC donation is a nonsurgical procedure and the most common way to donate. For 5 days leading up to donation, you will be given injections of a drug called filgrastim to increase the number of cells in your bloodstream that are used for transplant. Some of your blood is then removed through a needle in one arm and passed through a machine that separates out the blood-forming cells. The remaining blood is returned to you through the other arm. 

Bone marrow donation is a surgical, usually outpatient procedure. You will receive anesthesia and feel no pain during the donation. Doctors use a needle to withdraw liquid marrow from the back of your pelvic bone via two small punctures.

Watch the video below to see a Lauren’s experience with donation 

The patient's doctor chooses the donation method that is best for the patient.

FACT: There are few risks to donating.

It is a common misconception that donating blood stem cells is dangerous. The truth is that there are actually very few risks in donating blood stem cells!

Protecting the safety of our donors and maintaining the public’s trust is essential to saving lives.

All donors are carefully prescreened to ensure they are healthy and the procedure is safe for them.

There are rarely any long-term side effects from donating either PBSC or marrow. The donor’s immune system stays strong, and their blood stem cells replenish themselves in 4 to 6 weeks.

While no medical procedure is completely risk free, every precaution is taken to ensure the safety and well-being of the donor.

Because only 1 to 5% or less of your marrow is needed to save the patient’s life, your immune system stays strong.

FACT: It doesn’t take long to save someone’s life.

It’s actually a myth that the donation process takes a long time!

Online registration takes about 10 minutes. Completing and returning a cheek swab kit only takes a few minutes.

If you’re called to donate, the typical time commitment for the donation process is 20-30 hours spread out over a four-to- six-week period. This includes phone calls, appointments and the donation.

Akeem, peripheral blood stem cell (PBSC) donor

FACT: Donation is absolutely free to the donor.

Many people think that donating to a patient in need is expensive for them, but Be The Match covers every cost related to donation!

Be The Match covers travel, meals and hotel for donors and one companion.

All medical costs for the donation procedure are covered by the patient’s medical insurance or Be The Match.

FACT: We protect your privacy and confidentiality.

Sharing your personal information and DNA sample with us is NOT risky, because Be The Match has rules in place to protect your privacy.

Maintaining your trust is essential to saving lives. That’s why your personal identifying information will not be shared with any companies or government agencies.

We have rules in place to protect the rights and privacy of both donors and patients.

Information about your genetic type and the stored sample from your cheek swab are identified by a code and stored separate from your personal identifying information.

FACT: Ethnic background is an important factor for matching donors and patients.

Patients are most likely to match someone of the same ethnic background. That’s because genetic type is inherited.

Adding more registry members who increase the ethnic diversity of the registry increases the variety of tissue types available, helping more patients find the match they need.

Searching patients especially need more donors who identify as:

Black or African American American

Indian or Alaska Native

Asian, including South Asian

Native Hawaiian or other Pacific Islander

Hispanic or Latino


FACT: Members of the LGBTQ+ community CAN join the registry and donate.

It is a common misconception that gay men and other members of the LGBTQ+ community cannot join the registry or donate blood stem cells, when the reality is the exact opposite!

Be The Match does not ask about members’ sexual orientation.

For medical reasons, transsexual and non-binary individuals are asked to provide their sex assigned at birth when they register. Should you be called as a match, pronouns and gender identity are respected throughout the process.

FACT: Age guidelines protect the safety of the donor and provide the best possible outcome for the patient. They are not meant to discriminate.

Some believe that the age guidelines we have in place are to discriminate against those 45 and older. However, these guidelines are meant to protect the safety of the patient AND the donor.

Donors between the ages of 18 & 44 provide the greatest chance for transplant success.

Doctors request donors in the 18-44 age group 86% of the time.

Total cost to add a new member to the Be The Match Registry is about $100. To best serve patients and demonstrate responsible stewardship over the funds entrusted to us, we require individuals age 45+ to cover their own cost to join. There are many ways you can help even if donation is not an option:


Host a drive


Spread the word

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